Real Madrid v Galatasaray; UEFA Champions League quarter-final first leg, Santiago Bernabeu; Wednesday 3rd April; 19:45 KO
Real Madrid boss Jose Mourinho rested key players at the weekend including the likes of Xabi Alonso, Angel Di Maria and Mesut Ozil - all are set to return.
Teenage sensation Raphael Varane and full-back Fabio Coentrao also missed the game against Real Zaragoza with slight injuries, and are expected to return to the line-up.
However, Madrid legend Iker Casillas will be sitting on the bench after not fully recovering from a hand injury, which means Diego Lopez will start in goal.
Former Bolton striker Johan Elmander is in the Galatasaray squad as he recovers from a foot injury which has seen the Sweden international out for two months.
Didier Drogba will spearhead the Turkish side's attack and Mourinho will know all about him after their time at Chelsea, but the Portuguese should be wary of Burak Yilmaz who is the joint top scorer in the competition.
Mourinho: 'They are not my my players, they are my friends'.
Jose Mourinho talks highly of his previous players, but does conclude that he must help his own players stop both Didier Drogba and Wesley Sneijder from having a great game in the Champions League quarter-final tonight (Wednesday).
The former Chelsea boss has described both Sneijder and Drogba, whom he managed at different points during his career, as his friends and believes both players are great ones, but was quick to say that the Ivorian was not the greatest that he had ever worked with.
The 50-year-old has never been one to shy away from showing his true feelings and has recently been linked with a sensational return to Stamford Bridge, where he enjoyed four years.
"I don't say Didier was the greatest player I have worked with because I have had so many great players," Mourinho said, according the The Guardian.
"But he was a great player, a great friend and somebody who will be part of my life forever. He would say the exact same about me. We created the kind of emotional links that are more than football."
"They were my players, we love each other and we respect each other. But we have completely conflicting objectives. They want to win and I want to win. I have to make help my players to make sure that they do not have a great game.
"They are two great players in my career, two important players. But now they are not my players – they are my friends."