The 19-year-old moved to the DW Stadium during the January transfer window, with the intention of gaining some regular first-team football in Roberto Martinez's side.
But, as the Latics became embroiled in a relegation battle, the Chilean international found game time hard to come by, meaning he was forced to settle for a place on the bench for much of the 2012/13 campaign.
Henriquez has now returned to Old Trafford where he will continue his development under the stewardship of new Manchester United manager David Moyes, but has not ruled out the prospect of rejoining Wigan for a second spell, even though they'll be operating in the Championship.
"I didn't play a lot of football, which was obviously the target when I arrived in January," the South American forward told the Wigan Evening Post.
"But just being involved with a Premier League team, living the experience of first team football and learning from other players and other teams has been very good.
"I have enjoyed my time here and I wouldn't rule out coming here again if that is a possibility. Who knows?"
Henriquez reflected positively on his time at Wigan, having also seen them win the FA Cup at Wembley after beating Manchester City earlier this month, and will now be looking to kick on again next season.
"You always improve and pick up new things from new managers and new players," he added. "That was the point of the whole exercise, and I hope to show what I've learned when I return to Old Trafford."