The 27-year-old defender has long been linked with a move away from the Mestalla, with a host of top European clubs courting his signature.
Paris Saint-Germain are said to be monitoring the France international's situation in Spain, after he recently snubbed Valencia's offer of a new and improved contract.
Rami has made no secret of his desire to test himself at the highest level, and will be looking to join a bigger club, if, and when an offer comes his way.
"I want to try something new," he told French radio station RMC. "I have two-years left on my contract, but if there is an interesting offer I could leave Valencia.
"My desire is to find a bigger club."
The Valencia star's latest comments are likely to fuel more speculation about his long-term future, with PSG and Manchester City set for a summer bidding war.