Sky Sports reports how the Portugal international has been linked with a move away from the Santiago Bernabeu this summer, following the recent departure of his compatriot Jose Mourinho.
Mourinho has been credited with an interest in bringing Pepe to Stamford Bridge, as he looks to strengthen Chelsea's defensive ranks as a priority ahead of the 2013/14 campaign.
Incoming Manchester City manager Manuel Pellegrini is also believed to be monitoring the 30-year-old centre-back's situation, as he prepares to bring the Real Madrid star to the Etihad Stadium.
However, both clubs will face a serious fight to secure Pepe's signature, after Perez reiterated Real Madrid's stance that he is unavailable for transfer, to Chelsea, Manchester City or anywhere else.
"Pepe is for for sale and will not move this summer, at least that's my opinion," the Real supremo told Onda Cero.
Perez also responded to speculation surrounding the respective futures of Cristiano Ronaldo and Iker Casillas, saying that neither player is likely to leave La Liga this summer.
"I never said he wanted to go," he added when asked about Ronaldo. "And I cannot imagine a future without Casillas."