Andy Murray's preparations for this month's US Open suffered a set back after a shock defeat to Ernests Gulbis, his first loss since May.

Unfortunately for the man from Dunblane, his second match in this year's Rogers Cup was one to forget, as the world No. 38 pulled off a surprise straight sets win 6-4 6-3. 

It took the Latvian an hour and 28 minutes to proceed to the quarter finals.

There was nothing to separate the players throughout much of the opening set, with Murray missing the chance to collect the first break of the match in the seventh game, as Gulbis held firm. 

And this proved critical as the Latvian then broke Murray at 5-4, to edge the opening set.  

The 24-year-old continued to frustrate Murray, and once again broke the Wimbledon champion to take a 3-1 lead at the start of the second. 

Murray wasn't going to be beaten easily, and the Brit hit back immediately taking the next two games to level at 3-3. 

But two games later Murray was back in the dog house after a superb slice from Gulbis sealed a second break point to give him a 5-3 lead. 

Murray's chances of making a comeback for the second time were written off in the ninth game as Gulbis sealed victory with an ace.

It is the first time Gulbis has beaten Murray after five straight defeats to the world No. 2.  

Murray returned to the court on Wednesday after finally sealing his first Wimbledon title back in July. 

His main rival, Novak Djokovic, went through to the quarter finals after a three set win over Denis Istomin 2-6, 6-4, 6-4. The Serbian is up against world No. 7, Richard Gasquet, on Friday afternoon.

After Thursday's defeat to Gulbis, the Scotsman will need to shine at next week's Cincinnati Masters to get himself ready for the last Grand Slam of the season.


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