Daniel Sturridge scored his third consecutive winner for Liverpool as Brendan Rodgers' side defeated north-west rivals Manchester United.
Sturridge - who was celebrating his 24th birthday - scored the winner in the fourth minute as he took his tally to three goals in three games.
Manchester United manager David Moyes, who was looking for his first win at Anfield, was dealt a blow in his preparations to the game as Wayne Rooney was ruled out of the match after picking up a cut to his head in training.
Moyes' problems worsened after just four minutes when Daniel Agger met a Steven Gerrard corner before flicking it onto Sturridge - who headed home from close-range.
Manchester United were continually frustrated by Liverpool's resilient defence which resulted in Red Devils trio Tom Cleverley, Michael Carrick and Robin van Persie picking up yellow cards during the opening 45 minutes.
The Premier League champions started the second half strongly and had a penalty call turned down when Danny Welbeck went on a surging run down the left before going down in the box - after being legitimately marshalled off the ball by Iago Aspas.
Moyes threw on Portuguese winger Nani and Javier Hernandez as his side went in search of an equaliser but the duo were unable to have an impact on the result.