Daniel Sturridge's groin injury is likely to keep him out for Tuesday's World Cup qualifier with Ukraine and maybe even Liverpool's Premier League clash with Swansea next weekend, reports BT Sport.
Sturridge returned to the Liverpool for further treatment on the problem picked up in Sunday's Premier League clash with bitter rivals Manchester United where he headed in the winner after four minutes.
That goal was his fifth of the season in four games as he also netted against Stoke City and Aston Villa and recorded a brace in his side's League Cup victory against Notts County.
The 24-year-old was ruled out earlier this week for Moldova's visit to Wembley, but now, England manager Roy Hodgson has cast further doubts over his strikers fitness.
"We have to be honest here," said the England manager.
"Sturridge is doing ever so well to try and make himself available.
"He was devastated to turn up injured. He wanted to be with us and to have the treatment so he could play.
"But the fact is when they did the scan at the beginning of the week, it was going to be touch and go for Tuesday, and possibly even Saturday week.
"He wants to be a part of it. He's young and can recover quickly. We hope there's some good news on Sunday morning and he can come with us and take part.
"But I'm not enormously optimistic. I'm not confident. We can't put him out there unless he is fit."
The former Chelsea striker has endured a frustrating start to his international career, he has just six caps to his name since making his debut in 2011.
His development was stunted at the Blues by a lack of game time, but a move to Liverpool has reinvigorated his career.
The Manchester City youngster was picked for games against the Republic of Ireland and Brazil earlier in the summer but picked up an injury in the first game against Ireland and spent the summer recovering.
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