Chelsea have an 8.90% chance of winning the 2013/14 Champions League, while Manchester United only have a 6.40% chance of lifting the trophy, according to a BSports mathematics and data-driven algorithm.
The computer simulator predicts that Barcelona are most likely to be crowned European champions in Lisbon next May.
The Catalan giants, now managed by Gerardo Martino, have a 21.30% chance of winning the tournament - a whole 2.40% more likely than the reigning European champions Bayern Munich, who are now coached by Pep Guardiola, in second place.
Spanish giants Real Madrid, meanwhile, only have a 16.70% chance of winning their first Champions League trophy since 2002, despite the arrival of world-record signing Gareth Bale from Tottenham.
Manchester City have a 7.20% chance of securing their first ever Champions League title - a whole 0.80% chance more than their neighbours, who have reached three finals since 2008.
Arsenal, though, do not make the top six. However, the Gunners are expected to qualify for the knockout rounds of the competition, rather as the favourites to secure qualification from Group F ahead of Borussia Dortmund, Napoli and Marseille.
Barcelona | Chances of winning: 21.30%
Bayern Munich | Chances of winning: 18.90%
Real Madrid | Chances of winning: 16.70%
Chelsea | Chances of winning: 8.90%
Manchester City | Chances of winning: 7.20%
Manchester United | Chances of winning: 6.40%