Former Manchester United star Gary Pallister believes David Moyes' approach to the Capital One Cup tie with Liverpool would have changed after the champions were heavily beaten against arch rivals Manchester City this past weekend.
United went down by four goals to one at the Etihad on Sunday, and Pallister believes Moyes would have had a rethink on his team selection following the defeat.
He now believes United's clash with Brendan Rodgers' Liverpool takes an even greater importance.
Speaking to Sky Sports News, Pallister said: "The Man City game is going to hurt, that's for sure.
"To lose four to your arch-rivals is hard to take so I'm sure the manager might have changed his thoughts over the last 24 hours as to what team he puts out on Wednesday night. All of a sudden I think that game becomes a little bit more important."
The former United defender does have sympathy for Moyes as he believes the early season fixtures have not been kind to the Old Trafford outfit.
Pallister continued: "What a tough start to the season they've had in terms of the first five Premier League games; Chelsea at home, Liverpool away and Man City away. I've never known such a tough start to a fixture list for Manchester United since I played at the club.
"It has been difficult."
United will be desperate to put on a show in-front of their own crowd tomorrow night in a game that should also mark the return of controversial Liverpool forward Luis Suarez.
The Uruguayan international will make his first competitive appearance in a Reds shirt after being given a 10-match ban for biting Chelsea defender Branislav Ivanovic towards the end of last season.
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