It may only be the League Cup, but Liverpool need a victory here more than they have at any other point of the season so far.
After such an encouraging start, the last three halves of football they have been involved in have been really poor.
Swansea's showing last Monday in the second half put the blinkers on Brendan Rodgers' men and that form carried into the weekend just gone where Southampton made The Reds' look timid and the visitors came away with the three points.
You could say that the Anfield outfit had afforded themselves a poor result after the first three games where they won 1-0 in each, including against tonights opponents Manchester United.
But one thing is obvious, they have been rattled and the Saints showed that it could be difficult to shake out of that mindset.
Therefore, a clash against their fierce rivals could be the making or breaking of them in terms of meeting their lofty aims of returning back to the Champions League come-what May.
This isn't a tie against a lower Premier League side nor is it against an alright Championship side, this is their biggest rivals and naturally, that adds importance and incentive.
If anything cracks them out of out of their current situation it is a match against the Red Devils but it could go one of two ways.
A win would be brilliant, it would prove that their early form was no fluke, it would show bounce-back ability, something that they haven't had to show until now.
It would boost morale at the perfect time with Luis Suarez coming back, the critics would be answered along with the skeptics who may question what sort of effect the Uruguayan will have on the side considering his recent behaviour.
If Liverpool really want to return to the days of success or at least to those where they genuinely challenge for titles then they have to look at winning every game.
Of course, they cannot win every game, that is impossible, not even the Barcelona's, Real Madrid's or Bayern Munich's of the world can do that, but that has to be the mindset.
The 'it's only the League Cup' attitude wont suffice.
They aren't a team like (without trying to be unkind) Fulham, Sunderland or Norwich who can just dismiss this competition because it will conflict with Premier League interests.
Because just imagine if The Reds lose tonight.
All of a sudden, they haven't won in three games, they've lost a chance of silverware and the fans become unhappy at losing to their rival.
That would be shattering to any teams confidence and it would be even tougher to come back from that, and even more so to a side that are looking to reach the Champions League after a long absence.
You may look at some of the other top teams in England like Arsenal, Chelsea and Manchester United and still point out that they too have been known to field a weakened team both in this competition and the FA Cup.
However, managers like Arsene Wenger and Sir Alex Ferguson only do/did that when they think that side has a genuine chance of wining without any doubt at all, neither would send out a team that they know would lose because they have that win every game mentality as I mentioned.
The bottom line is that if Liverpool field a weakened side tonight at Old Trafford they will lose.
I would say there is almost no chance that David Moyes will field a weak side tonight, he is under even more pressure and will be desperate to win,and so will the players after two games and two defeats already to their biggest enemies.
Rodgers will know that, I think he is looking a terrific manager and the club are definitely turning a corner under his stewardship so hopefully he does the right thing tonight and goes for it or the whole season could go back to square one.
It sure to be an interesting game tonight....
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