Roberto Soldado v Gary Cahill
Spurs splashed £26 million to sign Spaniard Soldado from Valencia early this summer and the 28-year-old has provided a useful focal point for Villas-Boas' attack this season with a combination of physicality and goalscoring threat.
Despite his useful start, however, Soldado is yet to net from open play in the Premier League. Saturday's clash certainly wouldn't be a bad time to do just that, but he will be in for a tough 90 minutes against England international Cahill.
The former Bolton man has really grown in stature this season and is now considered as one of the first names on Mourinho's team-sheet.