Robbie Brady has withdrawn from the Republic of Ireland squad for their forthcoming World Cup qualifiers after being told he requires surgery to repair a groin injury sustained on Saturday.
The 21-year-old scored the decisive goal in Hull's 1-0 win over West Ham last weekend, but had to be substituted after 80 minutes after aggravating his groin.
He was still selected in temporary boss Noel King's first Ireland squad for the fixtures against Germany and Kazakhstan, but pulled out when a scan on Monday evening revealed the extent of the injury.
It will be a blow to King, who is watching over the side while the Irish Football Association search for a replacement to Giovanni Trapattoni, who departed by mutual consent earlier this month.
Brady has been in fine form for Hull since they returned to Premier League football and is the club's top goal-scorer with a tally of four goals, but the Tigers will now be without their winger for Saturday's game with Aston Villa.
Ireland boss King gave recalls to a trio of players that missed out under Italian Trapattoni, in his squad announced on Monday.
Among them was Darron Gibson, who has refused to play for the national side since the Italian left him on the bench for all of the Euro 2012 games.
If selected the Everton midfielder will play his first international match in over 16 months, his last game being as a substitute in a friendly draw with Hungary.
Also returning will be Anthony Stokes, Andy Reid and Kevin Doyle, who all fell out of favour with Trapattoni.
Meanwhile Jonathan Walters was selected for duty but may still miss out due to the groin injury sustained in Stoke City's defeat against Norwich on Sunday.
Ireland are fourth in Group C in Qualifying for the 2014 World Cup in Rio, but their hopes of qualifying for the tournament are all but over.
Republic of Ireland Squad:
Goalkeepers: David Forde (Millwall), Keiren Westwood (Sunderland), Darren Randolph (Birmingham)
Defenders: Joey O’Brien (West Ham), Sean St Ledger (Leicester), Marc Wilson (Stoke), Seamus Coleman (Everton), Stephen Kelly (Reading), Ciaran Clark (Aston Villa), Paul McShane (Hull)
Midfielders: Darron Gibson (Everton), Glenn Whelan (Stoke), James McCarthy (Everton), Paul Green (Leeds), Andy Reid (Nottingham Forest), Aiden McGeady (Spartak Moscow), Anthony Pilkington (Norwich), James McClean (Wigan), Stephen Quinn (Hull), Wes Hoolahan (Norwich)
Strikers: Shane Long (West Brom), Robbie Keane (LA Galaxy), Jon Walters (Stoke), Kevin Doyle (Wolves), Anthony Stokes (Celtic).
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