Ashley Cole has been ruled out of England's final World Cup qualifier against Poland on Tuesday, after failing to recover from a rib injury.
The 32-year old missed Friday's 4-1 win over Montenegro and has failed to recover in time.
Everton's Leighton Baines is likely to retain his spot at left-back as Roy Hodgson's side go into Tuesday's match at Wembley knowing a win will secure qualification to Brazil in 2014.
As well as Cole's absence, Hodgson will also have to replace suspended Kyle Walker, whose needless yellow card against Montenegro ruled the right-back out of contention.
Manchester United's Chris Smalling and Phil Jones are vying for the vacant right-back position.
Hodgson is likely to keep the faith in goalscoring debutant Andros Townsend, whose impressive performance at Wembley looks enough to hold on to the right wing.
Poland held the hosts to a 1-1 draw in Warsaw last year, a repeat scoreline could leave England facing the play-off route through to Brazil.
With potential to face off against the likes of France, Croatia, Sweden and Denmark.
Second place Ukraine stand currently one point behind England and are all but assured three points with their final game against 207th ranked San Marino.
San Marino have failed to win any points from their nine fixtures, shipping 46 goals in the process, the worst defensive record of all teams across the nine European groups.
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