Manchester United could be without star striker Robin van Persie for Saturday's Premier League match against Southampton at Old Trafford.
Red Devils' boss David Moyes has confirmed that Van Persie returned from international duty with a calf problem – and might not be fit to face fourth-placed Southampton this weekend.
The Dutchman was taken off at half-time during the Netherlands' 2-0 win over Turkey on Tuesday evening.
"We've got a few who came back with a few bumps and bruises," Moyes told MUTV. "Probably the one we're most worried about is Robin van Persie. We'll see how he is tomorrow.
"He got a kick in the calf and he came off at half-time in the second game. He also had problems with his toes as well. We'll see how he is."
The news is potentially a significant blow for Moyes, whose side currently sit ninth in the Premier League table after picking up a disappointing 10 points from their opening seven matches.
Van Persie, who has won the Premier League's Golden Boot award for the last two seasons running with Arsenal and Manchester United, became the Netherlands' all-time top scorer last Friday after netting a hat-trick in an emphatic 8-1 victory over Hungary.