Arsenal defender Per Mertesacker may be forced to miss both of Germany's international outings in the next week or so due to the illness that prevented him from taking part in the weekend defeat to Manchester United.
The centre-back was sent home prior to the 1-0 loss at Old Trafford on Sunday after contracting a flu-like condition and, reports Kicker, Mertesacker may now be unable to represent his country.
Mertesacker was supposed to join up with his international colleagues on Monday prior to the meeting with Italy later this week, but will instead remain in London to allow him further time to recover.
It remains unclear whether or not the 29-year-old will travel at all and may be omitted for the encounter against Italy on Friday, along with the match against England at Wembley four days later.
Mertesacker's absence was keenly felt by Arsenal at the weekend as Manchester United condemned the leaders to defeat, with TV analysis suggesting Robin van Persie may not have scored had the imposing German been on the pitch.
The former Arsenal captain scored the only goal of the game, a header from a corner in the 27th minute, to move David Moyes' side within five points of Arsenal.
The Gunners missed the opportunity to open a huge gap at the summit of the table after Chelsea drew on Saturday and both Manchester City and Tottenham suffered losses a day later.