Arsenal manager Arsene Wenger faces a delicate balancing act ahead of Sunday's FA Cup fifth round clash with Liverpool at the Emirates, as the Gunners look to exact instant revenge for last weekend's shock 5-1 defeat at Anfield.
Liverpool ran riot that afternoon after scoring four goals inside the opening 20 minutes, with the Reds continuing their charge towards title contention by humiliating Arsenal in stunning fashion.
Wenger's side have since responded with a solid but unspectacular 0-0 draw at home to Manchester United, but have lost Santi Cazorla for the Liverpool match through illness.
Cazorla's absence paves the way for Lukas Podolski to start in an advanced position on the left flank, or Tomas Rosicky to move across to the opposite flank, while Mathieu Flamini is back from a three-match suspension and will provide fresh legs in a congested midfield area.
Flamini will replace either Mikel Arteta, Jack Wilshere or Rosicky, while Lukasz Fabianski should fill in for Wojciech Szczesny in a rare start for the substitute goalkeeper.
Wenger also faces a difficult decision over whether to stick with Olivier Giroud in attack, with Nicklas Bendtner hoping to provide cover if Podolski doesn't start through the middle.
Alex Oxlade-Chamberlain is also likely to be included from the start, as Wenger reshuffles ahead of next week's Champions League showdown with Bayern Munich.
Liverpool meanwhile look likely to replace Kolo Toure with Daniel Agger in central defence, while Raheem Sterling will be hopeful of keeping his place alongside Luis Suarez and Daniel Sturridge in attack.
Arsenal starting XI: Fabianski, Gibbs, Mertesacker, Koscienly, Jenkinson, Flamini, Wilshere, Rosicky, Ozil, Oxlade-Chamberlain, Podolski
Liverpool starting XI: Mignolet; Flanagan, Cissokho, Skrtel, Agger; Gerrard, Coutinho, Henderson, Sterling; Sturridge, Suarez