Galatasaray v Chelsea
Similarly to Manchester United, Chelsea will surely go into their own first-leg last 16 tie as favourites - despite being away from home.
Galatasaray produced a solid performance to shock Serie A holders Juventus in the group stage and Roberto Mancini can call upon the likes of Wesley Sneidjer and former Blues favourite Didier Drogba.
An intimidating atmosphere surely awaits Jose Mourinho's side at Türk Telekom Arena, but once they get to grips with that they should emerge as comfortable victors heading back to Stamford Bridge.
PREDICTION - GALATASARAY 0-2 CHELSEA