This time it is the state of Arizona where the alleged offence took place, which can be added to charges he faces in Los Angeles and New Orleans.
Sharper is currently imprisoned in LA and is awaiting extradition to New Orleans to face one of his charges.
The former New Orleans Saints player already faces accusations in several states of drugging and raping women, and now he has been indicted in Arizona on sexual assault charges, Tempe police explained Wednesday.
Sharper played 14 years in the NFL, helping the Saints to a Super Bowl title in 2010.
In LA he is accused of drugging four women and raping two of them.
His accusations are of the same nature in Louisiana, and he is the subject of sex crimes investigations in both Florida and Nevada.