Arsenal midfielder Mesut Ozil will spend the next four weeks on the sidelines after scan results revealed significant damage to his hamstring, according to BBC Sport.
Ozil suffered the injury just a few minutes into Tuesday's Champions League last 16 second-leg clash with Bayern Munich, but played on until half-time regardless as the Gunners struggled in vain to keep their European dream alive.
The 25-year-old will now definitely miss a critical run of matches as Arsenal fight for silverware on two fronts, including this Sunday's North London derby against Tottenham Hotspur.
Huge league games against Manchester City and Chelsea will also be out of the German international's reach, while an FA Cup semi-final against Wigan Athletic on April 12th also looks a long shot in terms of full recovery.
Gunners boss Wenger now faces the prospect of being forced to shuffle an ever diminishing pack while still harbouring ambitions of an unlikely domestic double, all while Jack Wilshere and Theo Walcott remain on the long-term injury list.
Midfield maestro Aaron Ramsey and January signing Kim Kallstrom are also yet to feature in 2014, which has placed considerable strain on the likes of Mikel Arteta, Mathieu Flamini and Tomas Rosicky to plug the gap.
Despite being consistently attacked by critics during difficult spells in a topsy-turvy debut campaign Ozil's statistics suggest he will be sorely missed, scoring six goals and setting up a further 13 in 35 appearances for Arsenal across all competitions.
Arsenal can ill afford to be without a main who has been directly involved in 19-goals this season, but Wenger will need to rally the troops rather than dwell on absentees with the North London derby looming large this weekend.