Although the intriguing second legs of the Champions League's last 16 are in the forefront of everyone's mind at present, attentions must momentarily turn back to domestic action across the European continent this weekend.
While some - such as Bayern Munich, Paris-Saint Germain, Atletico Madrid and Barcelona - can rest easily now knowing that their places in the quarter-finals of club football's most-prestigious tournament are secure, others have the unenviable task on attempting to concentrate on league matters just days before their own European fate will inevitably be sealed.
As ever, there are some huge games around Europe's top leagues over the next three days, not least in the Premier League where we will see two enormous derby clashes take place on Sunday as second-placed Liverpool travel to face Manchester United at Old Trafford and an out-of-sorts Tottenham host Arsenal at White Hart Lane.
Ahead of such a vital weekend's action, we thought we would put a little twist on our usual pre-match predictions piece here at GMS.
Rather than mundanely just predict the overall outcome of the big fixtures, we thought we would change things up just a touch and instead choose eight predicted winners and losers.
So, without further ado, click on to see who we think will be the biggest winners and losers this weekend. There are five winners and three losers included in total.
As always, don't forget to leave your thoughts and opinions in the comment box provided below and tell us where you think we have got things right and where you believe we have gone wrong...