Referee Andre Marriner was involved in an embarrassing controversy at Stamford Bridge, as he sent off Arsenal's Kieran Gibbs instead of Alex Oxlade-Chamberlain in a 6-0 win by Chelsea.
Chamberlain handled Eden Hazard's shot with the score at 2-0, despite the fact it was going wide, and his assistant alerted him to the foul.
However, in an embarrassing mishap, Marriner sent off left-back Kieran Gibbs instead of his Arsenal and England colleague.
Arsene Wenger, in his 1000th game in charge, was forced to send on Thomas Vermaelen in place of Lukas Podolski to fill the gap at left-back, but Chelsea still romped to an impressive 6-0 victory.
The FA confirmed that Arsenal will be able to appeal the decision, although the likelihood is that while GIbbs will be eligible for Tuesday's game with Swansea, Chamberlain will have started a three-match ban.
The Football Association tweeted clubs "can appeal mistaken identity, although the FA can pro-actively review also".
Strangely, Marriner did not listen to Chamberlain when the young midfielder insisted that it was him who had committed the offence.
Following the defeat, Arsenal manager Arsene Wenger told press: "I believe it was handball but the referee hasn't seen it."
"The ball went out and I think it's Chamberlain who touched the ball. I don't know who gave indication to the referee that it was handball but he has certainly not seen it."
Chelsea manager Jose Mourinho, added: "There were lots of people in the box. Eden made a shot and you can clearly see a player dive like a goalkeeper touching the ball with his hand. From the bench you could not see what player it was. Someone said Arteta, it was Chamberlain, but the referee sent off Gibbs."
"It is the kind of situation where if you have a TV, the fourth official could see it was not Gibbs. Unfortunately the wrong boy came off."
UEFA president Michel Platini's spokesman quickly tweeted his views on the controversy, saying, "With an additional assistant referee on the end line, referee would not have got that sending off wrong. Technology is not the answer: more eye balls are the answer ... GLT (goal-line technology) helps with goal line decisions, but 5 officials system gives referee more angles of vision. It's not one vs the other."
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