The website pitted the opposing Super Bowl quarterbacks against each other in the first round of the tournament with Manning seeded 2nd and Wilson seeded 7th in the 'Right Now' bracket.
Fans were able to vote for who they believed to be the greater quarterback and in a 60-40% win, Wilson came out on top and knocked Manning out of the whole competition.
The bracket was split into four different eras. Brady, Manning and co are in the 'Right Now' bracket.
There is a bracket titled 'Generation X" which features Joe Montana (number one seed) and Dan Marino (number two seed).
The other two brackets are the 'Milenials' and the 'Baby Boomers', you can check it all out here.
Some of the favourites cruised through the opening round such as Montana winning by an incredible 98% of the vote and Tom Brady impressively defeated Eli Manning with 74% in their battle.
Although there were some shock exits in the first round, obviously Peyton Manning has already been mentioned but also Brett Favre and Troy Aikman were exiled despite their favoured seed in their contests.
Mirroring the NCAA tournament in real life, the 'Greatest Quarterback of All Time' bracket is now down to its sweet sixteen, voting closes for this round on Friday 26th March, so get involved quick and let us know who you think deserves to be the greatest signal caller of all time.