In a match that is crucial for both sides, victory is a must with Liverpool chasing the title and Spurs chasing Champions League football. Both will be hoping to put on memorable performance this afternoon at Anfield, with Spurs seeking revenge for their home thrashing at the hands of the Reds earlier this season.
There are no new injury concerns for either side, with defender Jose Enrique and Sebastien Coates still out for Liverpool with knee problems.
Reds boss Brendan Rodgers may well stick with the squad that beat Sunderland 2-1 on Wednesday.
For Tottenham, Emmanuel Adebayor is doubtful due to a gash on his heel, but does have a chance of making the squad.
Meanwhile, Kyle Walker, Erik Lamela, Vlad Chiriches and Étienne Capoue all remain on the sidelines due to continuing injury problems.
In the previous encounter between these two sides, Liverpool ran away with the game and walked out of White Hart Lane with a 5-0 victory, after which then Spurs boss André Villas-Boas was sacked and replaced with Tim Sherwood.
Liverpool know a win will all but secure their season objective of a top four finish, whereas Spurs have the incentive to take a step closer to fourth-placed Arsenal who dropped another two points yesterday against Manchester City.
Liverpool: Mignolet; Johnson, Agger, Skrtel, Flanagan; Gerrard, Henderson, Allen, Coutinho; Suárez, Sturridge.
Tottenham: Lloris; Naughton, Kaboul, Vertonghen, Rose; Bentaleb, Dembélé Lennon, Chadli, Eriksen; Soldado.
Write for GiveMeSport! Sign-up to the GMS Writing Academy here: http://gms.to/1a2u3KU