Orlovsky is expected to replace Shaun Hill as the backup to franchise QB Matthew Stafford in Detroit. The 30 year-old veteran played five years for the Lions between 2005 and 2008, featuring in 10 games during Detroit's disastrous 0-16 season in 2008.
After leaving Detroit in 2008, Orlovsky served as the third-string quarterback for the Houston Texans before playing eight games for the Colts in 2011 when Peyton Manning was out with an injury.
He played twice for the Tampa Bay Bucanneers last season. Orlovsky has thrown for 2,931 yards, 14 touchdowns and 12 interceptions during his career.
Matthew Stafford, the first overall pick in 2009, led the Detroit Lions to a 7-9 record last season, the team have made just one playoff appearance since 1999.