Any lingering hopes that Chelsea harbour of successfully reaching the semi-finals of the Champions League appear to have been given a big boost after Paris Saint-Germain owner Nasser Al-Khelaïfi claimed it would be 'impossible' for the striker to return from injury in time for the second leg.
32-year-old Ibrahimovic limped off the field with a hamstring problem with around 20 minutes remaining of PSG's comfortable 3-1 victory over the Blues at Parc des Princes on Wednesday and it appears that if the problem could sideline him for a number of weeks yet.
"We are waiting for the results of his tests," Al-Khelaïfi was quoted by The Guardian.
"But I think he will be absent for a minimum of four weeks. He will not be playing in
the return match against Chelsea, it's impossible."
While Ibrahimovic surprisingly did not play much of an integral role in a PSG victory that was wrapped up courtesy of goals from the impressive Ezequiel Lavezzi, Javier Pastore and an unfortunate OG from David Luiz, Chelsea's defenders will still surely be buoyed by the news that they will not have to face the powerful Swede again this season.
Regardless of that, however, Chelsea still have it all to do if they are to defy the odds and overturn the deficit to reach the last four of the tournament at Stamford Bridge on Tuesday night.
Although they do have the lifeline of an away goal that was secured via an Eden Hazard spotkick, Chelsea were lifeless in attack and often calamitous in defence earlier this week - not an ideal combination against one of European football's emerging superpowers, I am sure you will agree.
And while Jose Mourinho's side should not be ruled out of the tie completely by any means, it is going to be a hugely difficult task.
However, without the talismanic Ibrahimovic leading the line for their opponents, Chelsea might just have a fighting chance.