29-year-old Mascherano joined the Catalan giants back in 2010 yet has seen his future come under scrutiny with Barcelona not having quite lived up to expectations this season.
Sunday's goalless draw at home to Elche - coupled with Atletico Madrid's result against Malaga - ensured that the La Liga race will go down to the final game of the season and Mascherano has admitted that their decider against Diego Simeone's side could be many players' last game for Barcelona.
"We gave everything we had against Elche. They are a team that is fighting hard to avoid relegation."We now hope to win the Liga title at home against Atletico. It will all be decided next week," Mascherano said.
"It could be the last game for Barcelona for some of us."
If Mascherano were indeed to exit the Nou Camp this summer, it would not be a surprise to see plenty of Premier League interest build in his signature.
Liverpool - the club whom Mascherano left to join Barcelona in the first place - will be only too aware of his enduring qualities and the Argentine international's experience would be perfect for Brendan Rodgers as he plots to strengthen the squad ahead of the return of Champions League football to Anfield.
Arsenal, meanwhile, could also benefit from Mascherano's versatility, with the former River Plate, Corinthians and West Ham man having proved himself capable of performing adequately at centre-back as well as in midfield of late.