Arsenal are facing up to their biggest challenge of the Premier League season so far when Manchester City make the trip to north London for the early kick-off on Saturday.
The Gunners have famously struggled against the top teams in the Premier League, taking just 26 points out of a possible 90 against top-four clubs in recent seasons. However, there is hope that new signing Danny Welbeck can provide the killer instinct Arsenal need up front.
Meanwhile Manchester City are looking to bounce back from their shock 1-0 defeat to Stoke City but are likely to do so without their early season star Stevan Jovetic.
Welbeck to start
Most of the attention will surround Arsenal's new £16 million striker Welbeck. The England international made the controversial move from Manchester United on transfer deadline day and is set to make his full debut.
Welbeck should start ahead of Yaya Sanogo, who, despite scoring three goals in two games for France Under-21s this week, will drop to the bench as a result. Sanogo has had a productive week with the national youth side, but Welbeck's two goals for England against Switzerland should see him favoured.
Both Mesut Ozil (ankle) and Aaron Ramsey (ankle) were major injury concerns for this game but both midfielders were seen in full training on Friday morning suggesting they will be fit to start. Laurent Koscielny has also shaken off an Achilles injury ahead of the game while Kieran Gibbs is in contention after recovering from a hamstring strain
Mikel Arteta (ankle) and David Ospina (thigh) are being assessed while Theo Walcott and Serge Gnabry remain sidelined with respective knee injuries.
Manchester City are still waiting to see if Fernando (groin) and Jovetic (hamstring) come through late fitness tests. Pablo Zabaleta is hopeful of recovering from an ankle injury, imposed by Arsenal forward Lukas Podolski in Argentina's friendly against Germany, in time.
Arsenal have already got one over the Citizens this season after thrashing them 3-0 in the Community Shield. The Gunners were the dominant side on the day, but City fans can point to a weakened team as a potential reason for the defeat.
The Gunners have garnered five points from their games against Crystal Palace, Everton and Leicester while Manchester City are sitting above them with six.
Predicted team line ups
Arsenal: Szczesny; Debuchy, Mertesacker, Koscielny, Monreal; Arteta, Wilshere, Ramsey; Sanchez, Ozil, Welbeck.
Manchester City: Hart; Zabaleta, Kompany, Mangala, Kolarov; Silva, Nasri, Toure, Fernandinho; Aguero, Dzeko