Arsene Wenger has confirmed Yaya Sanogo will miss the game against Borussia Dortmund with a slight hamstring injury.
The 21-year-old played twice for France's Under-21 team during the international break, scoring three goals, but returned to London Colney with the affliction. He missed the game against Manchester City and Wenger has confirmed he is out of contention for Tuesday's tie.
Speaking to reporters ahead of the Champions League group game, Wenger confirmed: "Sanogo stayed at home with a little hamstring problem."
Sanogo will now join a lengthening list of Arsenal players currently on the injury list. It also leaves the Gunners with just one recognised striker in Danny Welbeck.
Giroud and Sanogo will not be alone on fitness expert Shad Forsythe's treatment table. Mathieu Debuchy is facing several months out after damaging his ankle ligaments in the game against Manchester City while Nacho Monreal is also out of tomorrow with a slight problem.
Wenger has also confirmed that Calum Chambers has only a 50 per cent chance of playing against Borussia Dortmund tomorrow after falling victim to tonsillitis. The string on injuries has left Arsenal perilously close to a real crisis in defence.
Kieran Gibbs will be back in the squad alongside Per Mertesacker and Laurent Koscielny but an injury to any of those players will leave Wenger with no other option but to delve into the youth team.
Hector Bellerin has received praise for his performances at right-back for the Under-21 side but a no centre-backs look close to competing for a first team place. Wenger confirmed as much as well as confirming that Monreal will be able to cover at centre-back.
He said: "Monreal can play centre-back and we have as well Bellerin, who I think is now ready to play."
Unfortunately, the injury problems bring to light Wenger's failure to sign a centre-back in the summer. Arsenal sold Thomas Vermaelen while Bacary Sagna and Carl Jenkinson also departed. Only Chambers was brought in, leaving the Gunners vulnerable.
It appears Wenger has been punished already. It begs the question what this Arsenal team would look like if Welbeck was not signed on the final day on the transfer window.
Arsenal fans may well be counting the days to the January transfer window already.