Tottenham's new summer signings Michel Vorm, Benjamin Stambouli and Federico Fazio could all be set to make their full debuts against Partizan Belgrade in the first group stage clash of the new Europa League campaign on Thursday night.
Encouragingly for Spurs, big-money striker Roberto Soldado is also set to play after returning from a back and neck injury that has forced him out of the last two games.
The Spaniard has travelled with the squad and played a full part in training on Wednesday night, suggesting he is ready for an appearance.
On Soldado, Tottenham boss Mauricio Pochettino said he was "okay, he's fully fit and maybe tomorrow he will have the chance to play."
Some notable omissions from the squad include Emmanuel Adebayor, Nacer Chadli, Mousa Dembele, Younes Kaboul and Danny Rose who have all remained in London.
Additionally, Pochettino commented on Kyle Walker's situation, saying he is recovering well after surgery.
Most exciting perhaps is the possibility to see Vorm and Fazio get their Tottenham careers off to a start, as well as Stambouli although he made his Premier League debut against Sunderladn as a substitute.
Pochettino has stated he will be taking the Europa League seriously and that it is a priority for the Club, so it will be expected for them to win tomorrow night at the Partizan Stadium.