And we've decided to whet the appetite for this weekend's clash by producing this concise player-by-player comparison feature. We've rated all 22 players expected to start this weekend out of 10 and compared them to find how which of the stars from both sides would make it into a combined XI.
We want your views
Fans from both United and Chelsea might be left upset by some of the selections. But we're eager to hear your views. Have we underrated or overrated any of the players? Are the scores fair or unfair? Tell us by leaving a comment in the box below.
We can all agree on one thing, though. This weekend's match will surely be more exciting than last season's corresponding fixture, back in August 2013, when the two sides played out a dire 0-0 draw in David Moyes' first home match in charge of the Red Devils.
Don't miss this match!
With a host of the world's best players in action - and both Louis van Gaal and Jose Mourinho battling for tactical supremacy - this promises to be one match you can't afford to miss.
And before you continue, please note: some of the players have been shifted about, position wise, in order to make a direct comparison with one of their counterparts.
Click on 'Begin Slideshow' to see the player-by-player comparison...