Steve Bruce will be wary of the frighteningly impressive Southampton side that will travel to the KC Stadium on Saturday.
Although, Hull have shown great strength against the teams towards the peak of the table thus far this season. Consecutive away draws at the Emirates and Anfield will boost the Tigers' confidence ahead of the visit of Ronald Koeman's in form Saints squad.
Bruce is expected to name the same line up that began the match against Liverpool where a desperate point was commendably held onto. That means that highly rated Scottish full back Andy Robertson will be left out of the squad once more, unveiling Hull's more attacking options with Robbie Brady.
Eldin Jakupovic is expected to start in between the posts again after last weeks impressive clean sheet, although the clean sheet may not have been had the Swiss keeper not denied Coutinho's rifling effort in the dying moments.
Michael Dawson and Nikica Jelavic will both sit the game out after picking up injuries in Hull's 2-2 draw with Arsenal respectively.
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Mane to miss out
There is only just one fresh injury concern for the visitors, and it is last week's match winner Sadio Mane who will miss out with an ankle strain after also sitting out their Capital One Cup tie with Stoke during the week.
James Ward-Prowse and Tottenham Hotspur target Jay Rodriguez will once again miss out through long term injuries.
Pelle on fire
But why should the Saints gaffer worry about injuries with a player like Graziano Pelle in his team? The 29-year-old joined the southern based side for £8 million from Feyenoord where their manager-player chemistry was so indestructible. And it seems as though it is turning out that way for Southampton too with 6 goals in 9 appearances for the Italian.
But Koeman will also be aware of Hull's threatening presence across the field. Summer signings Abel Hernandez and Mo Diame have made an instant impact in East Yorkshire, scoring a combination of 7 goals between them since joining the club on deadline day.
Hull's assistant manager Steve Agnew said "Southampton are by far the team of the season so far. We are aware of that and we shall adjust the way we play to make sure we can deal with them."