A good derby is not always about what happens on the pitch. The best of football rivalries are made in the stands by the fans but, from time to time, this intensity can boil over.
Police are said to be on "red alert" ahead of United's short journey to the blue side of Manchester and will be specifically on the look-out for drones, a key disruption in football of late caused by the fans.
You may remember in the previous international break that the tie between Serbia and Albania had to be cut short after a fan let their drone loose above the pitch.
A Serbian player then did the sensible thing to bring the drone out of the air, which resulted in a mass brawl between the two squads.
These drones are usually seen carrying a flag or a message which is provocative to the opposition which evidently causes trouble amongst the supporters.
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A more recent case of this coincidently happened at the Etihad Stadium when a Spurs fan was arrested outside of the ground for flying a drone after their 4-1 defeat against City.
The Daily Mail report that several Manchester United fans have recently served banning orders and are ready to return to battle against their noisy neighbours, causing plenty of trouble on their travels.
This would not be the first time there has been trouble in this derby. Two years ago, Rio Ferdinand was injured when he was pelted with coins, one of which caught him above the eye where blood was drawn.
Sniffer dogs will be used at the Etihad Stadium to seek out any flares that fans may bring to the game, which at this moment in time seems most likely.
But supporters are becoming more cunning and devious in their plans to scurry these dangerous items into football grounds. A bundle of flares were thrown onto the pitch in Arsenal's Champions League match against Galatasaray at the Emirates Stadium, where the game had to be momentarily halted.