The main question that will be flying around Neil Warnock's head right now is how he should set up and approach his sides' visit to Old Trafford tomorrow. The Eagles will be without their captain Mile Jedinak who was shown a red card in Palace's 3-1 loss to Sunderland on Monday night.
Wilfried Zaha will also be eligible to play against his parent club. So what does Neil Warnock have to look at? Well, United's defence is a key area of weakness at the moment. Marcos Rojo is injured with a dislocated shoulder suffered in the feisty Manchester derby last weekend while Chris Smalling is suspended from picking up a double yellow card in that fixture.
Louis van Gaal will also have to make do without fellow defenders Rafael, Phil Jones and Jonny Evans all through injuries so Michael Carrick and Antonio Valencia are expected to continue with their defensive duties which were carried out against City.
With a unserdy and makeshift defence, United will be certainly prepared for a bombardment of attacks from the visitors. However, Wilfried Zaha who leads the line of attack will be absent from the game and therefore the responsibility will fall into the hands of the rapid winger Yannick Bolasie who will be expected to feed Fraizer Campbell up front.
Palace must also be extremely wary defensively themselves with United's frightening attacking prospectus which includes players such as Angel Di Maria, Robin van Persie and Wayne Rooney. Falcao will miss the game through injury as Louis van Gaal ponders the opportunity to send him back to AS Monaco, cutting his loan move short.
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After making his return on Monday night against the Black Cats, Scott Dann is expected to organise the back line along with Joel Ward, Martin Kelly and Brede Hangeland who performed so poorly in their 3-1 defeat to Gus Poyet's side.
Neil Warnock will have to hope that luck is on his side for Saturday ahead of the game as the Eagles have never beaten Manchester United in the Premier League. In those 10 fixtures, Palace have failed to score in eight.
However, with United's shameful dip in form of late, could Crystal Palace's fortune be about to change?