Hartson, 39, believes the Gunners are in desperate need of a new holding midfielder because he does not feel that Mikel Arteta or Abou Diaby are reliable enough.
However, the retired Wales international is confident that summer signing Calum Chambers - a defender by trade - could eventually play in that position in the future.
Hartson speaks out
"A defensive midfield player should offer protection,” Hartson told Goal. "I like Mikel Arteta but he doesn't have the presence, while Abou Diaby can't string matches together.
"I see Calum Chambers eventually playing there but the summer buy from Southampton is needed elsewhere just now.”
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Hartson: Wenger must sign Khedira
Hartson went on to explain that either Khedira or Bayern Munich’s Javi Martinez would be perfect signings for the Gunners’ current squad - and that Wenger shouldn’t think twice about spending the money if the right target becomes available.
“Real Madrid's Sami Khedira has been linked and, although it would cost them £40 million to get his signature, Arsenal have the money and can't afford not to spend it,” he added. "If they can't get him, Javi Martinez at Bayern Munich would fit the bill."
Arsenal fans losing faith
Some Arsenal fans are beginning to lose faith in their long-serving manager following a disappointing start to the season. The Gunners have taken 17 points from their opening 11 matches, leaving them 12 points behind league-leaders Chelsea, who Wenger believes will win the Premier League title.
Last weekend’s 2-1 defeat to Swansea City was another bitter blow for Wenger, prompting further questions about whether the veteran French coach is still the right man for the top job at the Emirates Stadium.
Defensive midfield has certainly proved to be a problem position for the Gunners. it’s widely accepted that the team are in dire need of a first-class holding midfielder to close the gap on the likes of Chelsea and Manchester City.
Khedira a wanted man
For years Arsenal worked on a tight budget, but that’s changed in recent seasons. Wenger smashed the club’s transfer record on Mesut Ozil, an international teammate of Khedira’s, in the summer of 2013, and spent over £30 million on Alexis Sanchez earlier this year.
Khedira has been linked with a host of top clubs - including Manchester United, Manchester City and Chelsea - but Hartson believes Wenger can ill-afford to miss out on signing the German World Cup winner.