Olivier Giroud will not be able to participate in Arsenal's Champions League campaign unless they qualify for the knockout stages after Arsene Wenger chose not to register him for the tournament, reports The Mail.
The France striker will now miss Wednesday's game against Borussia Dortmund as well as the away tie to Galatasaray. With Arsenal needing just one point to secure their place in the last-16, they are still expected to qualify.
Giroud returned unexpectedly early from a broken ankle sustained against Everton on August 23. Uefa give clubs until August 31 to submit their 25-man squads and the decision was taken by Wenger to leave the 28-year-old out of the team.
Arsenal's medical staff had informed Wenger that the injury would likely rule Giroud out for the entire group phase with the earliest expected return date expected after match day five. However, Giroud returned against Manchester United on Saturday, scoring a superb consolation goal for the Gunners in the closing stages.
It is a self-inflicted blow that Wenger could do without. Arsenal are already in the midst of an injury crisis, although thanks to the acquisition of Danny Welbeck, the attacking line has been of little concern.
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Nevertheless, the French tactician is under pressure to beat Borussia Dortmund to give them some hope of finishing top of Group D. The Gunners will also need to get at least a point to secure qualification with a game to spare and Giroud would have granted Arsenal an extra dimension.
Jack Wilshere is also set to miss the tie against Borussia Dortmund after sustaining an ankle injury against Manchester United. The England midfielder was forced off in the second half after a heavy tackle from Paddy McNair.
Wilshere is set to receive results of a scan today but initial fears of a serious injury were eradicated after a preliminary scan revealed nothing was broken. However, ligament damage is still a possibility.
Wojciech Szczesny could also miss the game after suffering suspected concussion in a clash with Kieran Gibbs leaving the Gunners with the young and unproven Emiliano Martinez to fill in.