With only eight points on the board so far for Harry Redknapp's QPR, survival hopes are looking a little bleak in West London, and the injury of Sandro will knock the dreams of rescuing themselves back even further as the 25-year-old will have to sit out until the new year.
Before the Hoops fell behind against Newcastle at the weekend, Sandro was substituted in the 61st minute with what was first perceived to be a minor injury.
But speaking to the BBC, QPR club doctor Peter Florida confirmed that the injury was much more serious and Sandro will miss a worrying period of time.
"Sandro took a bad knock to his right knee, and has suffered damage to his medial ligaments" he confirmed.
Sandro has previously picked up an anterior cruciate ligament issue but Florida strongly stated that the injury had not been re-inflicted.
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The 25-year-old arrived at Loftus Road on deadline day for a hefty fee of £10 million where he was reunited with Harry Redknapp from Spurs where the Brazilian has made eight appearances.
Subsequent to Sandro's unwanted casualty he will miss key games against Leicester and December's hugely anticipated bundle of fixtures which include visits from Everton, Swansea and Arsenal, while he will also miss trips to Burnley, West Brom and Crystal Palace.
"It is a massive blow and it's horrible. He's a key player for us and without him we will really struggle. His positive influence on the team has spurred us on to get several points so far this season and without that I'm struggling to think of where we are going to pick up points from" Harry Redknapp told reporters in a press conference on Monday.
Rangers have only scraped eight points off the board this season, and although things remain tight towards to bottom end of the table, with a line of huge fixtures approaching to hit the strugglers head on, then picking up any more crucial points may be an uphill battle.