Manchester United boss Louis van Gaal has paired Wayne Rooney up front with Robin van Persie for the trip to St Mary's Stadium to face Southampton tonight.
The Old Trafford boss faces Dutch compatriot Ronald Koeman in the opposite dugout, with Van Gaal looking to jump his side ahead of the Saints with three points this evening.
Juan Mata and Marouane Fellaini also start for the visitors, while Southampton opt to go with Dusan Tadic, the Serbian recovering in time after suffering a knock.
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Forster, Clyne, Yoshida, Fonte, Bertrand, Long, Tadic, Wanyama, Davis, Mane, Pelle
Substitutes: Davis, Gardos, Mayuka, Isgrove, Reed, Targett, Hesketh
De Gea, McNair, Smalling, Rojo, Valencia, Carrick, Fellaini, Young, Mata, Rooney, van Persie
Substitutes: Lindegaard, Evans, Herrera, Fletcher, Januzaj, Wilson, Falcao