Whether you're watching in your warm living room as a neutral or inside Everton's collapsing fortress, one thing is guaranteed; a mouth watering slice of Monday night entertainment awaits.
Both sides are in urgent need of a boost, although Everton will be more prepared having failed to win in their previous three games. QPR on the other hand are starting to adapt to life back in the Premier League as Harry Redknapp's side come off the back of a 2-0 victory over relegation rivals Burnley.
Roberto Martinez will do everything he can to force influential midfielder James McCarthy back into the equation having missed out on a trio of fixtures, but Muhamed Besic is expected to keep his place due to the suspension of Gareth Barry after a collection of commendable performances.
Steven Naismith, Christian Atsu and Darron Gibson remain on the sidelines with injuries respectively while John Stones could make a return to the bench as he slowly recovers from an ankle strain.
Harry Redknapp will be without Sandro and Adel Taarabt until the new year while Alejandro Faurlin is out for the season.
Leading goalscorer Charlie Austin will also be sorely missed after picking up his first red card of the season against Burnley so Bobby Zamora is expected to deputise.
Steven Caulker may be risked, but with a juicy Christmas fixture list around the corner, the gaffer may be reluctant to rush the former Swansea defender back from a head injury.
Consistent form is proving to be a major concern for both managers as the duo have picked up just three wins in their previous six games put together so the stakes will be high on Merseyside ahead of the clash.
Rangers will be brimming with confidence after a storming triumph against Burnley last weekend whilst Everton are still recovering from a painstaking 1-0 defeat to the current holders, City.