Barcelona have had the transfer ban imposed by Fifa upheld by the Court of Arbitration for Sport which could now see the competitiveness of La Liga suffer as a result.
The Catalan giants will not be able to many any new signings next year, which could prove problematic in their bid wrestle the league title back from Diego Simeone's Atletico Madrid.
They remain free to negotiate new contracts with current members of the squad, though with several high-profile players eager to depart the Nou Camp may struggle to win silverware under Luis Enrique.
Barcelona were banned as a consequence for breaching regulations regarding the acquisition of foreign under-age players, though were allowed to make signings whilst the investigation was ongoing.
Goalkeepers Marc-Andre ter Stegan and Claudio Bravo were also drafted in to fill the void left by Victor Valdes' exit, with Jeremy Mathieu and Thomas Vermaelen arriving from Valencia and Arsenal.
Despite the club improving by the game under Enrique, uncertainty continues to surround members of the squad who could be on the move in the foreseeable future.
Martin Montoya is tickling the fancy of Serie A titans Juventus, though the Italian giants may face competition from Liverpool in the race for his signature.
Sergio Busquets has been an integral part of the side dating back to the days where Pep Guardiola ruled the roost, but Jose Mourinho is keen to bring him to Chelsea if John Obi-Mikel leaves the current Premier League leaders.
Rumours continue to persist that Dani Alves could make the move to England with Louis van Gaal's Manchester United, though superstar Pedro is likely to remain at the club after his manager blocked a potential move to Arsenal.
With Madrid currently in the midst of a 22-game winning run, Barcelona already face a difficult task in winning silverware this year.
Atletico have swooped to bring Fernando Torres back to the club, with the Spaniard being tipped by former England manager Fabio Capello to rediscover the goalscoring touch that may him so electrifying during his days at Anfield.
Barcelona and La Liga in general is now facing a difficult future. With Madrid so unstoppable, Carlo Ancelotti's side could dominate the Spanish scene for many years to come.