Jo-Wilfried Tsonga has pulled out of this month's Australian Open due to a forearm strain which forced him to withdraw from the Hopman Cup earlier this week.
Tsonga said: "I am still suffering from a forearm inflammation that prevents me being 100% in a competition."
The world number 12, who lost to Novak Djokovic in 2008's final is set to undergo over three weeks of treatment for the arm injury which has prevented him from competing.
World number three Rafael Nadal looks set to compete in this year's open since returning from appendix surgery. The Spaniard was defeated by British number one Andy Murray last Friday but will be hoping to rekindle the form which has seen him win 14 majors.
The injury to Tsonga has given Britain's James Ward hopes of featuring in this year's open a boost.
The British number two is currently one ranking point below the required entry level however may earn a place in the hat through another players' injury. Andy Murray comes into the Open in good form having seen off the big serving Jerzy Janowicz 6-2 6-4 in the Hopman cup tie against Poland.
Despite Murray's singles triumph, Poland won the tie against Britain and sit top of the group. Murray's shoulder injury looks to be healing well and the Scot has stated that as he plays more games it feels better and better.
The world number six and three time Australian Open finalist is currently 13/2 with SkyBet to go a step further this year and claim his third major title.