Manchester United boss Louis van Gaal has confirmed that Robin van Persie will miss this weekend's game against Sunderland.
The Dutch striker was seen leaving the Liberty Stadium on crutches after the 2-1 defeat against Swansea last weekend, and is also a major doubt for the Red Devils' FA Cup quarter-final against Arsenal in eight days time.
Speaking ahead of the game against Sunderland, Van Gaal said: "He [Robin] is the only injured player. He has an ankle injury. We have to wait and see how long that shall take."
With Van Persie absent, youngster James Wilson could be given a chance to shine in his place having shaken off a dead leg picked up in Manchester United's U21's game against the Black Cats on Monday.
It could also mean that Radamel Falcao is given an extended run in the first team if Van Gaal persists with deploying two strikers. The Colombian has failed to find his best form after completing his loan move from Monaco over the summer and has scored just four times in the Premier League.
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Michael Carrick is also in line to return to action having returned to training on Tuesday after overcoming a muscle rupture, however tomorrow's game may come too soon for him.
"He [Michael] is very experienced and he can play in a very important position," said Van Gaal. "But he also needs match rhythm. He trained only one time with us, with the group, so he needs to also play in the second team."
The Red Devils currently sit in fourth place in the Premier League, just three points clear of Tottenham in seventh after the defeat against Swansea. Sunderland meanwhile are just three points off the drop zone having won just two of their last ten league outings.
This really is now or never for Radamel Falcao. Manchester United have the option to make his transfer permanent for a £43 million at the end of the current campaign, and he has just 12 fixtures to show his worth. Although frankly put, his chances of impressing now are slim and even if he scores a hatful it may still no be enough.