Jack Wilshere ruled out of Manchester United clash - round-up

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Arsene Wenger has revealed an Arsenal injury blow for their crucial FA Cup quarter-final clash at Manchester United on Monday, as Jack Wilshere will not be ready for the clash at Old Trafford.

Speaking at the press conference ahead of Wednesday's Premier League meeting with QPR on Tuesday, the Gunners boss was asked about the current state of the young England midfielder's fitness and prospects for the meeting with Louis van Gaal's team.

Despite an operation Wilshere underwent last week to remove "two buttons" causing agitation in his ankle being described as "minor", it is enough to keep him sidelined for another two weeks. James Olley of the Evening Standard was at the press conference and Tweeted Wenger's reveal.

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Arsenal line up Brazilian star as replacement for Santi Cazorla

Wenger is also getting prepared to plan for the future of the Arsenal midfield outside of the likes of Wilshere, and it is man of the moment Santi Cazorla whose end s being envisaged.

According to the Daily Mirror, the Gunners have despatched scouts to keep a close eye on the progress of Roberto Firmino and the young Brazilian is being described as the most likely option from a number of targets, including the likes of Isco and Arda Turan.

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The Hoffenheim playmaker has been in fine form this season and the report claims Wenger feels he needs to plan the contingencies around the eventual departure of 30-year-old Cazorla. The Spaniard has been in his best vein of form since arriving at Emirates Stadium and fans may not be too comfortable with talk of him leaving.

Arsene Wenger signed a 'top five' player last summer, claims Arsenal Invincible

Former Gunners midfielder Edu has been lavishing praise on current star Alexis Sanchez, claiming that the £32million summer arrival from Barcelona could be one of the best five players in world football.

Edu was part of the famous 'Invincibles' squad from the 2004 Premier League season and has been very impressed by the Chilean's start at Arsenal. Sanchez exploded onto the scene earlier this season and is currently the club's top scorer with 18 goals in all competitions.

However, the physical duress of the game in England appears to be taking its toll in recent weeks, as Sanchez has not looked quite so lively and has failed to score in his last seven appearances.

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Premier League
Arsene Wenger
Jack Wilshere

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