Manchester United right-back Rafael will miss the rest of the season with a broken rib.
The Brazilian right-back was forced off during Manchester United U21’s 1-1 draw with Leicester City on Monday, after a collision with Anthony Knockaert.
Following the collision, Manchester United manager Louis van Gaal has moved to clarify the defender’s position on the treatment table.
"It's unbelievable," Van Gaal told MUTV. "He has broken his ribs so he shall not play any more this season for Manchester United. It's very unfortunate,” he told MUTV.
Despite Van Gaal’s claims, the loss of Rafael may not be as big of an impact as the Dutchman would suggest.
The identical-twin hasn’t started a game for seven months now, with his last United start coming in October.
Of more concern to the United boss with be injuries to Michael Carrick, Phil Jones and Marcus Rojo.
The defensive trio all missed last weekend’s defeat to Chelsea and will not feature in Saturday’s game at Goodison Park when the Red Devils face Everton.
Updates on other players
The only player that could make a comeback is Daley Blind, with the defensive-midfielder thought to be 50-50 for the tie.
"Only Blind maybe can reach the game against Everton but Jones, Carrick and Rojo cannot play," the Dutchman added.
Outcasted winger Adnan Januzaj will be available, despite coming off in the same game as Rafael on Monday night.
"[His injury] is not so heavy," Van Gaal said.
United travel to Goodison Park on Friday in good form, having won four out of their last five matches, including the 4-2 derby victory over Manchester City earlier this month.