Napoli and Lazio will battle it out at the Stadio San Paolo in the final game of the Serie A season to decide which of the two will play in next season's Champions League.
The team from the capital lie three points clear of their rivals, so a point would be enough for the Biancocelesti to secure a place in Europe's elite competition.
But a loss would see them switch places with Napoli who would qualify ahead of them due to a better head-to-head record.
Lazio could have secured their Champions League spot against city rivals Roma last weekend but an 85th minute winner denied that.
Manchester United be wary
Due to Lazio's lowly ranking within UEFA, it is very possible they may have to face Manchester United in a tricky qualifier.
This would be unwelcomed by fans of the Reds, as facing Lazio home and away would be a daunting prospect.
Lazio is a team full of quality and includes Premier League target, Feilipe Anderson, World Cup hero Miroslave Klose and Stefan de Vrij, who played under United coach Van Gaal for the Netherlands.
Napoli on the other hand, are ranked higher by UEFA and therefore would be unlikely to face the English giants, making it probable for both teams to face a lower calibre of opponent.
Strong home form
Napoli have made their home ground a fortress this season, only losing twice in 18 outings at the San Paolo.
They will be confident of keeping out Lazio and scoring themselves, with players such as Gonzalo Higuain and Marik Hamsik amongst their squad.
The last time these two sides met in Naples, it was Lazio who walked away with the three points and manager, Stefano Pioli will be confident of repeating that result.
Regardless of Champions League qualification, it looks extremely likely that Rafael Benitez will leave the club.
The Spaniard is as short as 1/20 with Sky Bet to leave Napoli and take over the reigns at Real Madrid. He will be tasked with bringing trophies to the Spanish capital after this years failure.
This will prove much more difficult than many would think.
Despite Los Blancos spending astronomical amounts of money in the last decade, they have only won the Champions League once in the past 12 years and only one La Liga title in the past seven seasons.
Should Benitez leave for pastures new, Manuel Pellegrini has been linked as a replacement if he doesn't survive at Manchester City after a difficult season.
Who do you think will qualify for the Champions League? Do you think Benitez could do a good job at Real Madrid? Give us YOUR opinion in the comment box below!