The talismanic Roma skipper missed the first leg of the quarter-final at the Stadio Olimpico on Tuesday with a thigh injury and without him the Giallorossi lost 2-0 to goals from Cristiano Ronaldo and Wayne Rooney.
And now Spalletti admits he is set to miss the Old Trafford rematch as well, saying after a 3-2 victory over Genoa: "I don´t think he will make it. Of course I would like to have a player like Totti available."
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