The second week of the 2015 NFL season was a tough one for quarterbacks, with a raft of veteran signal callers coming out of the weekend's action with injury concerns.
From Drew Brees (shoulder) and Tony Romo (fractured clavicle) to Matthew Stafford and Jay Cutler, there are a number of issues affecting big names stars heading into week three.
For the majority of those names listed, the timeline for recovery is unclear. We do know now, though, the extent of Jay Cutler's hamstring injury courtesy of NFL Media's Ian Rapoport.
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According to the NFL insider, the Chicago Bears will be without their starting quarterback for at least the next two games. To make matters worse for the Soldier Field franchise, Rapoport noted there are concerns Cutler's time on the sidelines could extend beyond week four.
Having made a solid, if not spectacular, start to the 2015 campaign, Cutler injured himself attempting to tackle Arizona Cardinals' Tony Jefferson as the safety returned an interception on Sunday afternoon.
In his absence, backup QB Jimmy Clausen completed 14-0f-23 passes for 121 yards and an interception - hardly the time of numbers to reassure a concerned fan base.
Clausen will now have to lead the Bears on the road against the Seattle Seahawks in week three before welcoming the Oakland Raiders to Chicago. Having not led an NFL team to a win since 2010, alarms bells are likely ringing for John Fox and co.
What's more, with the franchise staring down the barrel at a 0-2 start to the season, the loss of their starting quarterback only adds to a mounting list of casualties on offense.
Even before Cutler went down, the Bears have been without Alshon Jeffrey and Kevin White, whilst Eddie Royal has been dealing with his own hamstring issue.
Bears fans: Can your team cope without Cutler, and should a replacement QB be signed? Have your say in the comments below...
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