Stanislav Sestak put the home side ahead on the stroke of half-time and substitute Daniel Imhof made it 2-0 seven minutes from the end.
Hamburg, who had Vincent Kompany sent off on the hour mark, earned a lifeline through Rafael van der Vaart´s penalty in the 86th minute, but it was Bochum who secured the win to take them to the top of the Bundesliga.
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