Ferrari driver Sebastian Vettel aims to beat Mercedes driver Nico Rosberg to second in the Drivers' Championship, after Lewis Hamilton secured the Formula One title at last week's race in Austin.
The German is the only driver, other than the dominance of Mercedes' Hamilton and Rosberg, to win a Grand Prix this season and now hopes to pip his countryman to second, after the 30-year-old lost the title to his teammate last weekend.
The Ferrari driver told Sky Sports reporters: "For sure, second place is the target. First, unfortunately, is out of reach and second is better than third, so we'll try to go for second.
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"I want to beat Nico, that's the primary target that I have."
Vettel, 28, goes into the race weekend ahead of his compatriot by four points, in second, hoping to open up a points gap between himself and the third-placed Mercedes driver.
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Mercedes have dominated Formula One for the past two years and could come out on top again, with Hamilton looking to be the first driver to win at the Autodromo Hermanos Rodriguez circuit since it reopened after a 23-year spell away from the sport.
However, Vettel is looking forward to challenging 2015's World Champion for the top spot on the podium.
"I'm looking forward to getting out and feeling the track for the first time," Vettel added.
"The track looks very interesting, especially the fact that the altitude is playing a big role.
"Looking at the downforce levels of the cars and the drag levels, it should be an interesting experience."
The 28-year-old will be hopeful he can go one step further next season and win the title, with Ferrari expected to be more competitive as other teams continue to get used to the engine changes that were implemented at the beginning of last season.
Vettel could argue his car is the only reason the Drivers' Championship has come to an end as soon as it has, and had he been in Rosberg's Mercedes, he could have pushed Hamilton for the title right the way up to the season-ending race in Abu Dhabi.
In the three races Vettel has won this season, only once have Hamilton and Rosberg finished second and third behind him, suggesting the German has only won a Grand Prix once where Mercedes did not suffer reliability issues.
While Hamilton will be hoping to add to his tally of Grand Prix victories, focus will be on the two Germans battling it out with each other for second in the Drivers' Championship.