It is an unfamiliar situation for Manchester City leading up to kick off tonight, as a win in Seville could send them through to the knockout stages, providing Juventus do the business against Borussia Monchengladbach in Germany.
After usually doing things the hard way, City can potentially secure qualification with two games to spare.
A mighty task for the Citizens, their last victory in Spain came in their inaugural season in the Champions League four years ago with a 3-0 win against Villarreal.
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Of course, that was an entirely different outfit - hapless almost, unlike Sevilla. The Red and Whites caused a lot of problems in their recent meeting with City at the Etihad and were arguably unlucky not to come away with at least a point in the 2-1 defeat.
But what shape are both sides in heading into their bout at the Ramon Sanchez Pizjuan Stadium?
Some good news for Manuel Pellegrini as Gael Clichy - who is yet to make an appearance this season - has recovered from an ankle problem and has travelled with the squad.
Fabian Delph also makes his long-awaited return following a hamstring injury picked up on international duty for England. Sergio Aguero, Pablo Zabaleta, Samir Nasri and David Silva remain absent, though.
As for Sevilla, striker Kevin Gameiro will miss tonight's crunch clash after being stretchered off against Villarreal at the weekend.
Sergio Rico, Tremoulinas, Kolodziejczak, Rami, Coke, Krychowiak, N'Zonzi, Konoplyanka, Krohn-Dehli, Vitolo, Llorente.
Manchester City: 4-2-3-1
Hart, Sagna, Kompany, Otamendi, Kolarov, Toure, Fernandinho, Navas, De Bruyne, Sterling, Bony.
Since Sevilla and City's last clash, the Sky Blues are unbeaten in three - scoring seven goals and storming through to the quarter-finals of the Capital One Cup.
Meanwhile, their opposition's form has been mixed, a 5-0 win over Getafe was overshadowed by a loss to Villarreal.
A win for either side could potentially spell the end for their opponent's Champions League hopes so we should expect a tight and tense affair.
One thing is for sure, in order for the boys in blue to redeem their recent European failures, a loss is utterly unthinkable - no pressure.