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Steve Smith and Adam Voges made it four first-innings centurions for Australia before West Indies suffered a dramatic batting collapse as the hosts emphatically pressed home their advantage on day two of the Boxing Day Test at the Melbourne Cricket Ground.
Smith and Voges resumed on Sunday with Australia 345 for three, Joe Burns and Usman Khawaja having notched hundreds on Saturday, and continued to punish the lacklustre Windies attack. Smith was 134 not out and Voges unbeaten on 106 when the captain declared on 551 for three with an hour left of the afternoon session.
The home attack then showed their visitors there was some movement in the pitch, as the Windies crumbled from 35 without loss after tea to 91 for six at stumps.
James Pattinson, Nathan Lyon and Peter Siddle each snared two wickets apiece to leave the tourists - who lost the first Test by an innings and 212 runs - a massive 460 runs behind with just four first-innings wickets still standing.
The Windies began Sunday with a ball still fairly new and desperate to make inroads, but rarely looked like finding a breakthrough.
It was not the greatest batting spectacle, but the runs flowed steadily on a highly satisfactory day for Australia. Smith became the leading run-scorer in Tests this calendar year, while Voges moved past the 1000-run mark in his debut Test year and improved his career batting average against West Indies to 542.
Voges offered half a chance on 56 when he thick-edged a slower delivery from Test debutant Carlos Brathwaite towards first slip, but Darren Bravo - diving to his left - was unable to get to it and it ran away for four.
Smith, earlier this week named ICC Cricketer of the Year, completed his 13th Test hundred by picking up two runs off the part-time off-spin of Kraigg Brathwaite.
Thirty-six-year-old Voges followed his skipper in reaching three figures - his fourth Test ton - soon after with a neat flick to the right of mid-on off the bowling of Kemar Roach.
Australia were 527 for three at that point, and the declaration came two overs later.
West Indies' opening pair Kraigg Brathwaite and Rajendra Chandrika negotiated the 14 overs before tea without too much drama, and were 33 without loss at the interval - still trailing by a daunting 518.
But their stand was broken by the seventh ball of the evening's play, Brathwaite (17) inside-edging a tossed-up delivery from off-spinner Lyon straight to Burns at forward short leg.
Pattinson got himself among the wickets soon after, with two lbw scalps in as many overs. He first snared Chandrika for 25 with a reverse-swinging ball and then exposed Marlon Samuels' lack of footwork before he could trouble the scorers as he tried in vain to defend.
Jermaine Blackwood had to endure a nervous wait when, on 18, the umpires reviewed a low catch by Burns at short leg off the bowling of Siddle. Burns dived to his right, but the umpires decided it was not taken cleanly and Blackwood breathed a sigh of relief.
The 24-year-old Jamaican looked to have been set on making the most of his reprieve when he skipped down the track from the first ball of the following over and lofted Lyon over mid-off for six, but the off-spinner had his revenge four balls later when he dismissed the batsman caught and bowled.
That was not the end of the procession back to the Windies changing room either, with Siddle dismissing Denesh Ramdin and Jason Holder for ducks off successive deliveries at the start of the 41st over.
Carlos Brathwaite (three not out) kept out the hat-trick ball and he and Darren Bravo (13no) helped the away side through to the close without any more setbacks, but Australia will be hoping to wrap up the Windies' first innings quickly on day three.